Does Stem Cell Therapy Work For Autism Spectrum Disorder?

While behavioural therapy has been the first remedy strategy for autism, there are different modern approaches that may be utilised sooner or later. Find out all about it right here.

Written by Prerna Mittra |Updated : November 7, 2024 4:00 PM IST

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Regenerative medicine -- a medical approach that uses stem cells, tissues, biomaterials, and bioactive molecules to repair, change, or regenerate damaged cells, organs, and tissues to restore normal perform -- has made great strides in the healthcare area, with researchers seeking to faucet into its potential. On the subject of autism, whereas traditional therapies associated to behaviour and speech have been fashionable remedy options, newer medical improvements encourage to deal with the causes of its symptoms, says Dr Pradeep Mahajan, regenerative medicine researcher and founder of StemRx Hospital and Research Centre.

In keeping with the professional, autism spectrum disorder (ASD) is characterised by difficulties in social communication, the presence of stereotypical behaviour patterns and problems with sensory sensitivity. These factors can have a vigorous impression on a person's quality of life.

"Regenerative forms of medicine, together with stem cell therapies, have gotten well-liked in people with ASD, as a result of they've the potential to provide lengthy-lasting change," Dr Mahajan says. Also Read

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Traditional Approaches To Autism Treatment

Let us first understand the traditional approaches to treating autism. In line with the doctor, autism has been handled, taught and therapeutically managed with utilized behaviour analysis (ABA) and other forms of communication or occupational therapy. "Though effective, such interventions are all the time more of a behavioural approach; they don't search out potential biological causes. Hence for many families, this was never sufficient when it comes to effective change, which encouraged them to search for newer therapies," the skilled comments.

Regenerative Medicine And Stem Cell Therapy For Autism

A newer approach to remedy of autism includes the use of cells and their derivatives out there by way of regenerative therapy. The technique focuses on repairing or restoring the function of cells to counteract a number of the biological deviations contributing to signs of ASD. "Autism has so many biologic elements; it can't be managed just by therapeutics. Regenerative drugs opens up the possibilities of significantly bettering neurodevelopmental outcomes by targeting cellular dysfunctions," Dr Mahajan explains.

The knowledgeable explains that stem cell therapy employs stem cells' properties of maturation into specialised cells -- comparable to neural cells and tissue, as well as productions of development elements -- that stimulate cellular repair mechanisms and relieve inflammation. "There are research that claim that many people with ASD displayed neuro-inflammation, oxidative stress and improper functioning of the gut-brain axis. Such dysfunctions may clarify the peculiarities of a broad spectrum of phenomena spanning from impaired social and communicative abilities to disturbances of gastrointestinal well being, which are foreseeable in ASD."

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Clinicians look to regulate inflammation, alter the immune derivative response and consolidate neural networks and their features through the use of stem cells derived from bone marrow or umbilical remnants, the doctor explains, adding that doing this may increasingly help alleviate signs and improve cognitive efficiency, communication, and even behaviour.

Clinical Findings And Current Evidence

Preliminary clinical investigations have found stem cell therapy for autism to be promising. In keeping with the skilled, some patients have reportedly exhibited enhancements in language acquisition, social expertise, and eye contact after undergoing stem cell therapy. "Although these interventions are still termed as investigational, they provide expectations for patients looking for enhanced therapeutic alternatives to the standard medical therapies." TRENDING NOW

Beyond Stem Cells

Dr Mahajan says that along with stem cell therapy, regenerative medication contains different revolutionary interventions like intestinal microbiota switch (IMT), neuropeptides, and quantum vitality drugs -- methods that focus on optimising neurological health and balancing the intestine-brain axis, which is known to influence temper, behaviour, and cognition.

autismautism consciousnessAutism Spectrum DisorderRegenerative medicineStem cell therapy

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